Fuller's credits include cult indie film Red, White and Blue[2][3] and Creature,[4] with appearances in Law & Order:Special Victim’s Unit, CSI: Crime Scene Investigation, NCIS, 7th Heaven, Judging Amy, Boston Public, Buffy the Vampire Slayer, 8 Simple Rules, The Division, Touched by an Angel, Malcolm in the Middle, The Practice, L.A. Doctors, and That 70s Show, and a role in the graphic adventure game Frankenstein: Through the Eyes of the Monster. Fuller directed the Los Angeles production of the theatrical play This is our Youth written by Kenneth Lonergan starring Tyler Williams (of television’s Everybody Hates Chris). Fuller was a recurring guest star on the 2012 season of Grey's Anatomy on ABC.[5] In 2012, Fuller joined the cast of the ABC sitcom Last Man Standing starring Tim Allen. She currently portrays the role of eldest daughter Kristin Baxter, replacing Alexandra Krosney, who played the role in the show's first season. 
